Nonstop flights from Charlotte to St. Louis

2 airlines fly this route, with up to 6 flights a day.

CLTCharlotte Douglas International

574 mi · 34 flights a week

STLSt. Louis Lambert International

CLTSTL

When they leave

Charlotte time

7:32a9:45pFirst departure 7:32 AM, last 9:45 PM

Five in the morning, 7:32 AM to 11:50 AM, then three in the afternoon, 12:10 PM to 4:21 PM, then two in the evening, 5:58 PM to 9:45 PM.

Every flight

Earliest first

7:32 AM→8:31 AMAmerican AirlinesBoeing 737Sun
7:37 AM→8:33 AMAmerican AirlinesBoeing 737Tue
8:35 AM→9:32 AMAmerican AirlinesBoeing 737Mon, Wed, Thu, Fri, Sat, Sun
11:00 AM→12:00 PMAmerican AirlinesAirbus A319Tue
11:50 AM→12:45 PMSouthwest AirlinesBoeing 737 MAX 8Mon, Thu, Fri
12:10 PM→1:02 PMAmerican AirlinesBoeing 737Mon, Wed, Thu, Fri, Sat, Sun
1:35 PM→2:30 PMSouthwest AirlinesBoeing 737-700Sun
4:21 PM→5:21 PMAmerican AirlinesBoeing 737Tue
5:58 PM→6:59 PMAmerican AirlinesBoeing 737Daily
9:45 PM→10:40 PMAmerican AirlinesBoeing 737Daily

Schedules last checked Sep 19, 2026. Times are local.

Flying from Charlotte to St. Louis

American Airlines flies most often, 4 to 5 times a day on the Boeing 737 and Airbus A319. Southwest Airlines flies 4 times a week on the Boeing 737 MAX 8 and Boeing 737-700.

Flights run every day of the week, from 4 on Wednesdays and Saturdays to 6 on Sundays. The first arrival in St. Louis is at 8:31 AM and the last at 10:40 PM. The flight covers 574 miles.

Flying back, St. Louis to Charlotte has 33 nonstop flights a week.

Return flights

St. Louis to CharlotteView

Find the cheapest day to fly from Charlotte to St. Louis.

Schedules as of Oct 9, 2026.