Nonstop flights from Detroit to San Antonio
Delta Air Lines flies this route 2 to 3 times a day.
DTWDetroit Metropolitan Wayne County
1,215 mi · 20 flights a week
SATSan Antonio International
When they leave
Detroit time8:25a8:30pFirst departure 8:25 AM, last 8:30 PM
One morning flight at 8:25 AM, then one afternoon flight at 1:45 PM, then one evening flight at 8:30 PM.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Detroit to San Antonio
Delta Air Lines is the only airline flying nonstop from Detroit to San Antonio, 2 to 3 times a day on the Airbus A319.
There are 2 or 3 flights every day of the week. The first arrival in San Antonio is at 10:34 AM and the last at 10:34 PM. The flight covers 1,215 miles.
Flying back, San Antonio to Detroit has 17 nonstop flights a week.
Return flights
More from Detroit
Find the cheapest day to fly from Detroit to San Antonio.
Schedules as of Oct 9, 2026.