Nonstop flights from Sioux Falls to Chicago
2 airlines fly this route, with up to 7 flights a day.
FSDSioux Falls Regional
461 mi · 49 flights a week
ORDChicago O'Hare International
When they leave
Sioux Falls time6:24a6:39pFirst departure 6:24 AM, last 6:39 PM
Three in the morning, 6:24 AM to 11:12 AM, then two in the afternoon, 12:06 PM to 3:06 PM, then two in the evening, 5:23 PM to 6:39 PM.
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Earliest first
Schedules last checked Sep 21, 2026. Times are local.
Flying from Sioux Falls to Chicago
United Airlines flies most often, 4 times a day on the CRJ 700, Boeing 737 and Embraer 175. American Airlines flies 3 times a day on the CRJ 700.
There are 7 flights every day of the week. The first arrival in Chicago is at 8:30 AM and the last at 8:38 PM. The flight covers 461 miles.
Flying back, Chicago to Sioux Falls has 49 nonstop flights a week.
Return flights
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Schedules as of Oct 9, 2026.