Nonstop flights from Houston to St. Louis

Southwest Airlines flies this route 3 to 6 times a day.

HOUHouston William P. Hobby

687 mi · 32 flights a week

STLSt. Louis Lambert International

HOUSTL

When they leave

Houston time

5:30a10:40pFirst departure 5:30 AM, last 10:40 PM

Six in the morning, 5:30 AM to 11:05 AM, then three in the afternoon, 1:20 PM to 3:55 PM, then five in the evening, 5:10 PM to 10:40 PM.

Every flight

Earliest first

5:30 AM→7:30 AMSouthwest AirlinesBoeing 737 MAX 8Thu, Fri
6:40 AM→8:40 AMSouthwest AirlinesBoeing 737 MAX 8Sun
7:20 AM→9:20 AMSouthwest AirlinesBoeing 737 MAX 8Tue, Wed, Thu, Fri, Sat, Sun
7:20 AM→9:25 AMSouthwest AirlinesBoeing 737 MAX 8Mon
10:35 AM→12:40 PMSouthwest AirlinesBoeing 737 MAX 8Tue, Wed, Thu, Fri
10:40 AM→12:45 PMSouthwest AirlinesBoeing 737-700Mon
11:05 AM→1:05 PMSouthwest AirlinesBoeing 737 MAX 8Thu, Fri
1:20 PM→3:20 PMSouthwest AirlinesBoeing 737 MAX 8Mon
3:00 PM→5:00 PMSouthwest AirlinesBoeing 737Mon
3:55 PM→5:55 PMSouthwest AirlinesBoeing 737Tue, Wed, Sat, Sun
5:10 PM→7:10 PMSouthwest AirlinesBoeing 737-700Mon
5:55 PM→7:55 PMSouthwest AirlinesBoeing 737Tue, Wed, Sat, Sun
7:50 PM→9:50 PMSouthwest AirlinesBoeing 737-700Thu, Fri
9:00 PM→11:00 PMSouthwest AirlinesBoeing 737-700Sun
10:40 PM→12:45 AM⁺¹Southwest AirlinesBoeing 737 MAX 8Mon

Schedules last checked Sep 19, 2026. Times are local.

Flying from Houston to St. Louis

Southwest Airlines is the only airline flying nonstop from Houston to St. Louis, 3 to 6 times a day on the Boeing 737 MAX 8, Boeing 737-700 and Boeing 737.

Flights run every day of the week, from 3 on Saturdays to 6 on Mondays. The first arrival in St. Louis is at 7:30 AM and the last at 12:45 AM the next day. The flight covers 687 miles.

Flying back, St. Louis to Houston has 31 nonstop flights a week. George Bush Intercontinental (IAH) also has nonstop flights to St. Louis, 24 a week.