Nonstop flights from Chicago to San Francisco
Southwest Airlines flies this route twice a day.
MDWChicago Midway International
1,852 mi · 14 flights a week
SFOSan Francisco International
When they leave
Chicago time10:15a9:10pFirst departure 10:15 AM, last 9:10 PM
Two in the morning, 10:15 AM to 10:25 AM, then two in the evening, 7:15 PM to 9:10 PM.
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Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Chicago to San Francisco
Southwest Airlines is the only airline flying nonstop from Chicago to San Francisco, twice a day on the Boeing 737 MAX 8.
The first arrival in San Francisco is at 12:50 PM and the last at 11:45 PM. The flight covers 1,852 miles.
Flying back, San Francisco to Chicago has 14 nonstop flights a week. O'Hare (ORD) also has nonstop flights to San Francisco, 130 a week.
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Schedules as of Oct 9, 2026.