Nonstop flights from Milwaukee to St. Louis

Southwest Airlines flies this route 1 to 2 times a day.

MKEMilwaukee Mitchell International

318 mi · 13 flights a week

STLSt. Louis Lambert International

MKESTL

When they leave

Milwaukee time

6:15a5:25pFirst departure 6:15 AM, last 5:25 PM

Three in the morning, 6:15 AM to 8:20 AM, then two in the afternoon, 4:25 PM to 4:50 PM, then one evening flight at 5:25 PM.

Every flight

Earliest first

6:15 AM→7:30 AMSouthwest AirlinesBoeing 737 MAX 8Sat
8:00 AM→9:15 AMSouthwest AirlinesBoeing 737-700Mon, Thu, Fri, Sun
8:20 AM→9:35 AMSouthwest AirlinesBoeing 737-700Tue, Wed
4:25 PM→5:40 PMSouthwest AirlinesBoeing 737-700Tue, Wed
4:50 PM→6:05 PMSouthwest AirlinesBoeing 737Mon, Thu, Fri
5:25 PM→6:40 PMSouthwest AirlinesBoeing 737-700Sun

Schedules last checked Sep 19, 2026. Times are local.

Flying from Milwaukee to St. Louis

Southwest Airlines is the only airline flying nonstop from Milwaukee to St. Louis, 1 to 2 times a day on the Boeing 737-700, Boeing 737 and Boeing 737 MAX 8.

There are 1 or 2 flights every day of the week. The first arrival in St. Louis is at 7:30 AM and the last at 6:40 PM. The flight covers 318 miles.

Flying back, St. Louis to Milwaukee has 14 nonstop flights a week.

Return flights

St. Louis to MilwaukeeView

Find the cheapest day to fly from Milwaukee to St. Louis.

Schedules as of Oct 9, 2026.