Nonstop flights from Myrtle Beach to Chicago
2 airlines fly this route, with up to 3 flights a day.
When they leave
Myrtle Beach timeTwo in the afternoon, 12:04 PM to 3:24 PM, then two in the evening, 5:00 PM to 6:21 PM.
Every flight
Earliest firstSchedules last checked Sep 19, 2026. Times are local.
Flying from Myrtle Beach to Chicago
American Airlines flies most often, 1 to 2 times a day on the Embraer 170 and Embraer 175. United Airlines flies daily on the Embraer 175.
Flights run every day of the week, 3 on Saturdays and 2 on the other days. The first arrival in Chicago is at 1:37 PM and the last at 7:56 PM. The flight covers 753 miles.
American Airlines is back on Mar 4, 2027. United Airlines flies it until Oct 24 and is back on Dec 1.
Flying back, Chicago to Myrtle Beach has 15 nonstop flights a week. From Myrtle Beach, Midway (MDW) is the other Chicago area airport with nonstop flights, 7 a week.
Return flights
Every Chicago airport
More from Myrtle Beach
Schedules as of Oct 9, 2026.