Nonstop flights from Chicago to Kirksville
Contour Airlines flies this route daily.
ORDChicago O'Hare International
275 mi · 7 flights a week
IRKKirksville Regional
When they leave
Chicago time2:40p2:40pDeparts 2:40 PM
One departure, at 2:40 PM. It runs daily.
Every flight
Earliest first
Schedules last checked Sep 20, 2026. Times are local.
Flying from Chicago to Kirksville
Contour Airlines is the only airline flying nonstop from Chicago to Kirksville, daily on the CRJ.
The flight covers 275 miles.
Flying back, Kirksville to Chicago has 7 nonstop flights a week.
Return flights
Find the cheapest day to fly from Chicago to Kirksville.
Schedules as of Oct 9, 2026.