Nonstop flights from Fort Myers to Detroit
Delta Air Lines flies this route twice a day.
RSWFort Myers Southwest Florida International
1,086 mi · 14 flights a week
DTWDetroit Metropolitan Wayne County
When they leave
Fort Myers time12:22p5:49pFirst departure 12:22 PM, last 5:49 PM
Two in the afternoon, 12:22 PM to 2:15 PM, then one evening flight at 5:49 PM.
Every flight
Earliest first
Schedules last checked Sep 21, 2026. Times are local.
Flying from Fort Myers to Detroit
Delta Air Lines is the only airline flying nonstop from Fort Myers to Detroit, twice a day on the Airbus A321 and Airbus A321neo.
The first arrival in Detroit is at 3:20 PM and the last at 8:45 PM. The flight covers 1,086 miles.
Flying back, Detroit to Fort Myers has 14 nonstop flights a week.
Return flights
More from Fort Myers
Find the cheapest day to fly from Fort Myers to Detroit.
Schedules as of Oct 9, 2026.