Nonstop flights from San Diego to Chicago

3 airlines fly this route, with up to 13 flights a day.

SANSan Diego International

1,721 mi · 88 flights a week

ORDChicago O'Hare International

SANORD

When they leave

San Diego time

6:15a10:45pFirst departure 6:15 AM, last 10:45 PM

Six in the morning, 6:15 AM to 10:40 AM, then four in the afternoon, 1:03 PM to 4:08 PM, then three in the evening, 5:45 PM to 10:45 PM.

Every flight

Earliest first

6:15 AM→12:50 PMAmerican AirlinesBoeing 737 MAX 8Daily
6:18 AM→12:37 PMUnited AirlinesAirbus A321neoDaily
7:03 AM→1:22 PMAlaska AirlinesBoeing 737 MAX 9Daily
7:24 AM→1:54 PMAmerican AirlinesBoeing 737Daily
9:48 AM→4:23 PMAmerican AirlinesBoeing 737Daily
10:40 AM→4:59 PMUnited AirlinesBoeing 737 MAX 9Daily
1:03 PM→7:21 PMAlaska AirlinesBoeing 737-800Daily
1:11 PM→7:59 PMAmerican AirlinesAirbus A321Mon, Tue, Wed, Fri, Sat
1:11 PM→7:59 PMAmerican AirlinesAirbus A321Thu, Sun
2:15 PM→8:36 PMUnited AirlinesAirbus A321neoDaily
4:08 PM→10:14 PMUnited AirlinesBoeing 737Daily
5:45 PM→11:59 PMAlaska AirlinesBoeing 737Mon, Thu, Fri, Sun
10:40 PM→4:43 AM⁺¹United AirlinesBoeing 737 MAX 9Daily
10:45 PM→5:02 AM⁺¹American AirlinesAirbus A321Daily

Schedules last checked Oct 7, 2026. Times are local.

Flying from San Diego to Chicago

American Airlines flies 5 times a day on the Airbus A321, Boeing 737 and Boeing 737 MAX 8. United Airlines flies 5 times a day on the Airbus A321neo, Boeing 737 MAX 9 and Boeing 737. Alaska Airlines flies 2 to 3 times a day on the Boeing 737, Boeing 737 MAX 9 and Boeing 737-800.

There are 12 or 13 flights every day of the week. The first arrival in Chicago is at 12:37 PM and the last at 5:02 AM the next day. The flight covers 1,721 miles.

Flying back, Chicago to San Diego has 88 nonstop flights a week. From San Diego, Midway (MDW) is the other Chicago area airport with nonstop flights, 24 a week.