Nonstop flights from St. Louis to Chicago
3 airlines fly from St. Louis (STL) to 2 Chicago airports (ORD and MDW), with up to 20 flights a day.
Routes
2 airport pairs- STL to ORDSt. Louis Lambert to Chicago O'Hare13 to 15 a day
- STL to MDWSt. Louis Lambert to Chicago Midway3 to 5 a day
When they leave
St. Louis time10 in the morning, 6:00 AM to 11:25 AM, then seven in the afternoon, 12:59 PM to 4:54 PM, then six in the evening, 5:30 PM to 8:50 PM.
Every flight
Earliest firstSchedules last checked Sep 19, 2026. Times are local.
Flying from St. Louis to Chicago
United Airlines flies most often, 8 to 10 times a day on the CRJ 700, Airbus A319, Airbus A320, Boeing 737 and Embraer 175. American Airlines flies 5 times a day on the Embraer 170, Airbus A319, CRJ 700 and Embraer 175. Southwest Airlines flies 3 to 5 times a day on the Boeing 737 MAX 8, Boeing 737-700 and Boeing 737.
Flights run every day of the week, from 17 on Saturdays to 20 on Mondays, Wednesdays, Thursdays, Fridays and Sundays. The first arrival in Chicago is at 7:05 AM and the last at 9:55 PM.
STL to ORD is the busiest airport pair, with 102 flights a week, then STL to MDW with 33.
Flying back, Chicago to St. Louis has 135 nonstop flights a week.
Return flights
Schedules as of Oct 9, 2026.