Nonstop flights from Brussels to Istanbul

Turkish Airlines flies this route 4 to 5 times a day.

BRUBrussels

1,330 mi · 30 flights a week

ISTIstanbul

BRUIST

When they leave

Brussels time

7:20a6:50pFirst departure 7:20 AM, last 6:50 PM

Two in the morning, 7:20 AM to 11:10 AM, then two in the afternoon, 2:30 PM to 4:15 PM, then one evening flight at 6:50 PM.

Every flight

Earliest first

7:20 AM→11:45 AMTurkish AirlinesAirbus A321neoDaily
11:10 AM→3:40 PMTurkish AirlinesAirbus A321neoDaily
2:30 PM→6:55 PMTurkish AirlinesAirbus A321neoDaily
4:15 PM→8:45 PMTurkish AirlinesBoeing 737Fri, Sun
6:50 PM→11:20 PMTurkish AirlinesAirbus A321neoDaily

Schedules last checked Sep 12, 2026. Times are local.

Flying from Brussels to Istanbul

Turkish Airlines is the only airline flying nonstop from Brussels to Istanbul, 4 to 5 times a day on the Airbus A321neo and Boeing 737.

Flights run every day of the week, 5 on Fridays and Sundays and 4 on the other days. The first arrival in Istanbul is at 11:45 AM and the last at 11:20 PM. The flight covers 1,330 miles.

Flying back, Istanbul to Brussels has 30 nonstop flights a week.

Return flights

Istanbul to BrusselsView

Find the cheapest day to fly from Brussels to Istanbul.

Schedules as of Oct 9, 2026.