Nonstop flights from Istanbul to Brussels

Turkish Airlines flies this route 4 to 5 times a day.

ISTIstanbul

1,330 mi · 30 flights a week

BRUBrussels

ISTBRU

When they leave

Istanbul time

7:40a6:50pFirst departure 7:40 AM, last 6:50 PM

Two in the morning, 7:40 AM to 10:55 AM, then two in the afternoon, 12:45 PM to 3:05 PM, then one evening flight at 6:50 PM.

Every flight

Earliest first

7:40 AM→10:10 AMTurkish AirlinesAirbus A321neoDaily
10:55 AM→1:25 PMTurkish AirlinesAirbus A321neoDaily
12:45 PM→3:15 PMTurkish AirlinesAirbus A321neoFri, Sun
3:05 PM→5:30 PMTurkish AirlinesAirbus A330Daily
6:50 PM→9:25 PMTurkish AirlinesAirbus A321neoDaily

Schedules last checked Sep 19, 2026. Times are local.

Flying from Istanbul to Brussels

Turkish Airlines is the only airline flying nonstop from Istanbul to Brussels, 4 to 5 times a day on the Airbus A321neo and Airbus A330.

Flights run every day of the week, 5 on Fridays and Sundays and 4 on the other days. The first arrival in Brussels is at 10:10 AM and the last at 9:25 PM. The flight covers 1,330 miles.

Flying back, Brussels to Istanbul has 30 nonstop flights a week.

Return flights

Brussels to IstanbulView

Find the cheapest day to fly from Istanbul to Brussels.

Schedules as of Oct 9, 2026.