Nonstop flights from Buffalo to Charlotte
American Airlines flies this route 4 times a day.
BUFBuffalo Niagara International
546 mi · 28 flights a week
CLTCharlotte Douglas International
When they leave
Buffalo time6:50a6:59pFirst departure 6:50 AM, last 6:59 PM
One morning flight at 6:50 AM, then two in the afternoon, 12:56 PM to 4:49 PM, then one evening flight at 6:59 PM. Every flight runs daily.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Buffalo to Charlotte
American Airlines is the only airline flying nonstop from Buffalo to Charlotte, 4 times a day on the Boeing 737 and Boeing 737 MAX 8.
The first arrival in Charlotte is at 8:49 AM and the last at 9:00 PM. The flight covers 546 miles.
Flying back, Charlotte to Buffalo has 28 nonstop flights a week.
Return flights
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Schedules as of Oct 9, 2026.