Nonstop flights from Buffalo to Chicago

Southwest Airlines flies this route 2 to 3 times a day.

BUFBuffalo Niagara International

467 mi · 20 flights a week

MDWChicago Midway International

BUFMDW

When they leave

Buffalo time

8:00a7:10pFirst departure 8:00 AM, last 7:10 PM

Four in the morning, 8:00 AM to 11:45 AM, then one afternoon flight at 4:35 PM, then two in the evening, 7:00 PM to 7:10 PM.

Every flight

Earliest first

8:00 AM→8:35 AMSouthwest AirlinesBoeing 737-700Sun
8:35 AM→9:10 AMSouthwest AirlinesBoeing 737-700Mon, Tue, Wed, Thu, Fri, Sun
8:40 AM→9:15 AMSouthwest AirlinesBoeing 737 MAX 8Tue, Wed, Sat
11:45 AM→12:20 PMSouthwest AirlinesBoeing 737-700Mon, Thu, Fri
4:35 PM→5:15 PMSouthwest AirlinesBoeing 737-700Sat
7:00 PM→7:40 PMSouthwest AirlinesBoeing 737 MAX 8Sun
7:10 PM→7:45 PMSouthwest AirlinesBoeing 737-700Mon, Tue, Wed, Thu, Fri

Schedules last checked Sep 19, 2026. Times are local.

Flying from Buffalo to Chicago

Southwest Airlines is the only airline flying nonstop from Buffalo to Chicago, 2 to 3 times a day on the Boeing 737-700 and Boeing 737 MAX 8.

There are 2 or 3 flights every day of the week. The first arrival in Chicago is at 8:35 AM and the last at 7:45 PM. The flight covers 467 miles.

Flying back, Chicago to Buffalo has 20 nonstop flights a week. From Buffalo, O'Hare (ORD) is the other Chicago area airport with nonstop flights, 49 a week.

Return flights

Chicago to BuffaloView

Every Chicago airport

All Buffalo to Chicago flightsView

Find the cheapest day to fly from Buffalo to Chicago.

Schedules as of Oct 9, 2026.