Nonstop flights from Panama City to Houston
Southwest Airlines flies this route daily.
ECPPanama City Northwest Florida Beaches International
569 mi · 7 flights a week
HOUHouston William P. Hobby
When they leave
Panama City time5:10a6:50pFirst departure 5:10 AM, last 6:50 PM
One morning flight at 5:10 AM, then three in the evening, 5:15 PM to 6:50 PM.
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Earliest first
Schedules last checked Sep 8, 2026. Times are local.
Flying from Panama City to Houston
Southwest Airlines is the only airline flying nonstop from Panama City to Houston, daily on the Boeing 737 and Boeing 737-700.
The first arrival in Houston is at 7:00 AM and the last at 8:35 PM. The flight covers 569 miles.
Flying back, Houston to Panama City has 10 nonstop flights a week. From Panama City, George Bush Intercontinental (IAH) is the other Houston area airport with nonstop flights, 21 a week.
Return flights
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Schedules as of Oct 9, 2026.