Nonstop flights from Houston to Des Moines
United Airlines flies this route twice a day.
IAHHouston George Bush Intercontinental
803 mi · 14 flights a week
DSMDes Moines International
When they leave
Houston time11:55a8:05pFirst departure 11:55 AM, last 8:05 PM
One morning flight at 11:55 AM, then one evening flight at 8:05 PM.
Every flight
Earliest first
Schedules last checked Sep 20, 2026. Times are local.
Flying from Houston to Des Moines
United Airlines is the only airline flying nonstop from Houston to Des Moines, twice a day on the Embraer 175.
The first arrival in Des Moines is at 2:14 PM and the last at 10:30 PM. The flight covers 803 miles.
Flying back, Des Moines to Houston has 14 nonstop flights a week.
Return flights
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Find the cheapest day to fly from Houston to Des Moines.
Schedules as of Oct 9, 2026.