Nonstop flights from Santiago to São Paulo

3 airlines fly this route, with up to 15 flights a day.

SCLSantiago Arturo Merino Benitez International

1,625 mi · 96 flights a week

GRUSão Paulo/Guarulhos-Governor André Franco Montoro International

SCLGRU

When they leave

Santiago time

12:50a9:30pFirst departure 12:50 AM, last 9:30 PM

Two overnight flights, 12:50 AM to 4:45 AM, then seven in the morning, 5:00 AM to 11:45 AM, then four in the afternoon, 12:35 PM to 4:25 PM, then four in the evening, 7:00 PM to 9:30 PM.

Every flight

Earliest first

12:50 AM→5:40 AMLATAM Airlines ChileAirbus A321Daily
4:45 AM→9:40 AMSKY AirlineAirbus A320neoMon, Wed, Thu, Sat
5:00 AM→9:55 AMLATAM Airlines ChileAirbus A321Mon, Tue, Thu, Sat, Sun
5:10 AM→9:55 AMLATAM Airlines ChileBoeing 787Wed, Fri
7:15 AM→12:15 PMLATAM Airlines ChileAirbus A320Daily
8:15 AM→1:10 PMLATAM Airlines ChileAirbus A320Daily
10:15 AM→3:00 PMTurkish AirlinesAirbus A350-900Daily
10:55 AM→3:45 PMLATAM Airlines ChileAirbus A320Daily
11:45 AM→4:40 PMLATAM Airlines ChileAirbus A320Daily
12:35 PM→5:30 PMLATAM Airlines ChileAirbus A320Daily
1:00 PM→5:55 PMSKY AirlineAirbus A321neoMon, Wed, Fri, Sun
3:45 PM→8:45 PMLATAM Airlines ChileBoeing 787-9Daily
4:25 PM→9:20 PMLATAM Airlines ChileAirbus A321Daily
7:00 PM→11:55 PMLATAM Airlines ChileAirbus A321Daily
7:25 PM→12:20 AM⁺¹LATAM Airlines ChileAirbus A320Tue, Thu, Sat, Sun
8:45 PM→1:35 AM⁺¹LATAM Airlines ChileAirbus A320Mon, Tue, Thu, Sat, Sun
9:30 PM→2:25 AM⁺¹SKY AirlineAirbus A320neoTue, Sat

Schedules last checked Sep 19, 2026. Times are local.

Flying from Santiago to São Paulo

LATAM Airlines Chile flies most often, 10 to 12 times a day on the Airbus A320, Airbus A321, Boeing 787 and Boeing 787-9. SKY Airline flies 1 to 2 times a day on the Airbus A320neo and Airbus A321neo. Turkish Airlines flies daily on the Airbus A350-900.

Flights run every day of the week, from 12 on Fridays to 15 on Saturdays. The first arrival in São Paulo is at 5:40 AM and the last at 2:25 AM the next day. The flight covers 1,625 miles.

JetSMART stopped flying it after Sep 15.

Flying back, São Paulo to Santiago has 62 nonstop flights a week.

Return flights

São Paulo to SantiagoView

Find the cheapest day to fly from Santiago to São Paulo.

Schedules as of Oct 9, 2026.