Nonstop flights from Santiago to Panama City

Copa Airlines flies this route 5 to 6 times a day.

SCLSantiago Arturo Merino Benitez International

2,988 mi · 39 flights a week

PTYPanama City Tocumen International Airport Panama

SCLPTY

When they leave

Santiago time

12:06a11:22aFirst departure 12:06 AM, last 11:22 AM

Five overnight flights, 12:06 AM to 4:14 AM, then one morning flight at 11:22 AM.

Every flight

Earliest first

12:06 AM→5:55 AMCopa AirlinesBoeing 737 MAX 8Daily
12:43 AM→6:32 AMCopa AirlinesBoeing 737 MAX 8Daily
2:14 AM→8:03 AMCopa AirlinesBoeing 737 MAX 9Daily
2:56 AM→8:45 AMCopa AirlinesBoeing 737 MAX 8Tue, Thu, Fri, Sat
4:14 AM→10:03 AMCopa AirlinesBoeing 737 MAX 8Daily
11:22 AM→5:11 PMCopa AirlinesBoeing 737 MAX 9Daily

Schedules last checked Sep 19, 2026. Times are local.

Flying from Santiago to Panama City

Copa Airlines is the only airline flying nonstop from Santiago to Panama City, 5 to 6 times a day on the Boeing 737 MAX 8 and Boeing 737 MAX 9.

There are 5 or 6 flights every day of the week. The first arrival in Panama City is at 5:55 AM and the last at 5:11 PM. The flight covers 2,988 miles.

Flying back, Panama City to Santiago has 39 nonstop flights a week.

Return flights

Panama City to SantiagoView

Find the cheapest day to fly from Santiago to Panama City.

Schedules as of Oct 9, 2026.