Nonstop flights from Medellín to Panama City

Copa Airlines flies this route 6 to 9 times a day.

MDEMedellín Jose Maria Cordova International

337 mi · 54 flights a week

PTYPanama City Tocumen International Airport Panama

MDEPTY

When they leave

Medellín time

5:00a6:20pFirst departure 5:00 AM, last 6:20 PM

Six in the morning, 5:00 AM to 10:40 AM, then three in the afternoon, 12:40 PM to 4:30 PM, then one evening flight at 6:20 PM.

Every flight

Earliest first

5:00 AM→6:27 AMCopa AirlinesBoeing 737 MAX 8Daily
6:25 AM→7:52 AMCopa AirlinesBoeing 737Daily
8:35 AM→10:02 AMCopa AirlinesBoeing 737-800Mon, Thu, Sat
9:15 AM→10:42 AMCopa AirlinesBoeing 737 MAX 9Daily
10:35 AM→12:02 PMCopa AirlinesBoeing 737 MAX 9Mon, Tue, Wed, Sat
10:40 AM→12:08 PMCopa AirlinesBoeing 737 MAX 9Thu
12:40 PM→2:07 PMCopa AirlinesBoeing 737Daily
3:10 PM→4:37 PMCopa AirlinesBoeing 737-800Daily
4:30 PM→5:57 PMCopa AirlinesBoeing 737-800Mon, Tue, Wed, Sat
6:20 PM→7:47 PMCopa AirlinesBoeing 737-800Daily

Schedules last checked Sep 19, 2026. Times are local.

Flying from Medellín to Panama City

Copa Airlines is the only airline flying nonstop from Medellín to Panama City, 6 to 9 times a day on the Boeing 737-800, Boeing 737 MAX 9, Boeing 737 and Boeing 737 MAX 8.

Flights run every day of the week, from 6 on Fridays and Sundays to 9 on Mondays and Saturdays. The first arrival in Panama City is at 6:27 AM and the last at 7:47 PM. The flight covers 337 miles.

Flying back, Panama City to Medellín has 54 nonstop flights a week.

Return flights

Panama City to MedellínView

Find the cheapest day to fly from Medellín to Panama City.

Schedules as of Oct 9, 2026.