Nonstop flights from Des Moines to Miami

American Airlines flies this route 6 times a week, starting again Oct 10.

DSMDes Moines International

1,328 mi · 6 flights a week

MIAMiami International

DSMMIA

When they leave

Des Moines time

5:00a6:30aFirst departure 5:00 AM, last 6:30 AM

Two in the morning, 5:00 AM to 6:30 AM.

Earliest first

5:00 AM→9:17 AMAmerican AirlinesResumes Oct 10Embraer 175Mon, Tue, Wed, Thu, Sun
6:30 AM→10:54 AMAmerican AirlinesResumes Oct 10Embraer 175Sat

Schedules last checked Sep 15, 2026. Times are local.

American Airlines is the only airline flying nonstop from Des Moines to Miami, 6 times a week on the Embraer 175.

Flights run every day except Fridays. The first arrival in Miami is at 9:17 AM and the last at 10:54 AM. The flight covers 1,328 miles.

Flying back, Miami to Des Moines has 6 nonstop flights a week.

Schedules as of Oct 9, 2026.