Nonstop flights from Las Vegas to Louisville
Southwest Airlines flies this route daily.
LASLas Vegas Harry Reid International
1,619 mi · 7 flights a week
SDFLouisville Muhammad Ali International
When they leave
Las Vegas time7:55a6:15pFirst departure 7:55 AM, last 6:15 PM
One morning flight at 7:55 AM, then two in the afternoon, 1:10 PM to 4:15 PM, then one evening flight at 6:15 PM.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Las Vegas to Louisville
Southwest Airlines is the only airline flying nonstop from Las Vegas to Louisville, daily on the Boeing 737-700, Boeing 737 and Boeing 737 MAX 8.
The first arrival in Louisville is at 2:40 PM and the last at 1:00 AM the next day. The flight covers 1,619 miles.
Flying back, Louisville to Las Vegas has 7 nonstop flights a week.
Return flights
More from Las Vegas
Find the cheapest day to fly from Las Vegas to Louisville.
Schedules as of Oct 9, 2026.