Nonstop flights from Chicago to Louisville

2 airlines fly this route, with up to 9 flights a day.

ORDChicago O'Hare International

286 mi · 62 flights a week

SDFLouisville Muhammad Ali International

ORDSDF

When they leave

Chicago time

6:56a9:25pFirst departure 6:56 AM, last 9:25 PM

Three in the morning, 6:56 AM to 10:35 AM, then five in the afternoon, 2:00 PM to 4:30 PM, then three in the evening, 5:59 PM to 9:25 PM.

Every flight

Earliest first

6:56 AM→9:38 AMUnited AirlinesEmbraer 175Daily
8:05 AM→10:35 AMAmerican AirlinesEmbraer 170Daily
10:35 AM→1:11 PMUnited AirlinesCRJ 700Daily
2:00 PM→4:38 PMUnited AirlinesEmbraer 175Mon, Tue, Wed, Thu, Sat
2:00 PM→4:36 PMUnited AirlinesCRJ 700Sun
2:07 PM→4:45 PMUnited AirlinesEmbraer 175Fri
3:24 PM→6:00 PMAmerican AirlinesEmbraer 175Mon, Tue, Wed, Thu, Fri, Sun
3:59 PM→6:35 PMAmerican AirlinesEmbraer 175Sat
4:30 PM→7:07 PMUnited AirlinesEmbraer 175Mon, Tue, Wed, Thu, Fri, Sun
4:30 PM→7:06 PMUnited AirlinesCRJ 700Sat
5:59 PM→8:36 PMUnited AirlinesEmbraer 175Daily
6:50 PM→9:25 PMAmerican AirlinesEmbraer 175Daily
9:25 PM→11:59 PMUnited AirlinesEmbraer 175Mon, Tue, Wed, Thu, Sat, Sun

Schedules last checked Sep 19, 2026. Times are local.

Flying from Chicago to Louisville

United Airlines flies most often, 5 to 6 times a day on the Embraer 175 and CRJ 700. American Airlines flies 3 times a day on the Embraer 175 and Embraer 170.

There are 8 or 9 flights every day of the week. The first arrival in Louisville is at 9:38 AM and the last at 11:59 PM. The flight covers 286 miles.

Flying back, Louisville to Chicago has 62 nonstop flights a week. Midway (MDW) also has nonstop flights to Louisville, 17 a week.

Return flights

Louisville to ChicagoView

Every Chicago airport

All Chicago to Louisville flightsView

Find the cheapest day to fly from Chicago to Louisville.

Schedules as of Oct 9, 2026.