Nonstop flights from Cali to Panama City
Copa Airlines flies this route 4 to 5 times a day.
CLOCali Alfonso Bonilla Aragón International
434 mi · 33 flights a week
PTYPanama City Tocumen International Airport Panama
When they leave
Cali time5:02a6:27pFirst departure 5:02 AM, last 6:27 PM
Two in the morning, 5:02 AM to 8:48 AM, then two in the afternoon, 12:08 PM to 3:12 PM, then one evening flight at 6:27 PM.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Cali to Panama City
Copa Airlines is the only airline flying nonstop from Cali to Panama City, 4 to 5 times a day on the Boeing 737.
There are 4 or 5 flights every day of the week. The first arrival in Panama City is at 6:34 AM and the last at 7:59 PM. The flight covers 434 miles.
Flying back, Panama City to Cali has 33 nonstop flights a week.
Return flights
More from Cali
Find the cheapest day to fly from Cali to Panama City.
Schedules as of Oct 9, 2026.