Nonstop flights from Cartagena to Panama City

Copa Airlines flies this route 4 to 5 times a day.

CTGCartagena Rafael Núñez International

280 mi · 31 flights a week

PTYPanama City Tocumen International Airport Panama

CTGPTY

When they leave

Cartagena time

6:20a7:00pFirst departure 6:20 AM, last 7:00 PM

Three in the morning, 6:20 AM to 9:45 AM, then two in the afternoon, 12:00 PM to 3:05 PM, then one evening flight at 7:00 PM.

Every flight

Earliest first

6:20 AM→7:40 AMCopa AirlinesBoeing 737Daily
9:25 AM→10:45 AMCopa AirlinesBoeing 737Mon, Thu, Fri
9:45 AM→11:05 AMCopa AirlinesBoeing 737Daily
12:00 PM→1:20 PMCopa AirlinesBoeing 737Tue, Wed, Fri, Sat
3:05 PM→4:25 PMCopa AirlinesBoeing 737Daily
7:00 PM→8:18 PMCopa AirlinesBoeing 737Mon, Thu, Sun

Schedules last checked Sep 19, 2026. Times are local.

Flying from Cartagena to Panama City

Copa Airlines is the only airline flying nonstop from Cartagena to Panama City, 4 to 5 times a day on the Boeing 737.

Flights run every day of the week, 5 on Mondays, Thursdays and Fridays and 4 on the other days. The first arrival in Panama City is at 7:40 AM and the last at 8:18 PM. The flight covers 280 miles.

Flying back, Panama City to Cartagena has 31 nonstop flights a week.

Return flights

Panama City to CartagenaView

More to Panama City

Find the cheapest day to fly from Cartagena to Panama City.

Schedules as of Oct 9, 2026.