Nonstop flights from Houston to Panama City
United Airlines flies this route 3 times a day.
IAHHouston George Bush Intercontinental
1,775 mi · 21 flights a week
PTYPanama City Tocumen International Airport Panama
When they leave
Houston time9:59a2:24pFirst departure 9:59 AM, last 2:24 PM
Two in the morning, 9:59 AM to 11:59 AM, then one afternoon flight at 2:24 PM. Every flight runs daily.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Houston to Panama City
United Airlines is the only airline flying nonstop from Houston to Panama City, 3 times a day on the Boeing 737 MAX 9 and Boeing 737.
The first arrival in Panama City is at 2:14 PM and the last at 6:37 PM. The flight covers 1,775 miles.
Flying back, Panama City to Houston has 10 nonstop flights a week.
Return flights
More from Houston
Find the cheapest day to fly from Houston to Panama City.
Schedules as of Oct 9, 2026.