Nonstop flights from Los Angeles to Des Moines
American Airlines flies this route daily until Nov 12, then again from Nov 28.
LAXLos Angeles International
1,445 mi · 7 flights a week
DSMDes Moines International
When they leave
Los Angeles time12:37p12:37pDeparts 12:37 PM
One departure, at 12:37 PM. It runs daily.
Every flight
Earliest first
Schedules last checked Sep 8, 2026. Times are local.
Flying from Los Angeles to Des Moines
American Airlines is the only airline flying nonstop from Los Angeles to Des Moines, daily on the Embraer 175.
The flight covers 1,445 miles.
Flying back, Des Moines to Los Angeles has 7 nonstop flights a week.
Return flights
More from Los Angeles
Find the cheapest day to fly from Los Angeles to Des Moines.
Schedules as of Oct 9, 2026.