Nonstop flights from Knoxville to Washington
American Airlines flies this route 2 to 3 times a day.
TYSKnoxville McGhee Tyson
436 mi · 20 flights a week
DCARonald Reagan Washington National
When they leave
Knoxville time7:04a7:31pFirst departure 7:04 AM, last 7:31 PM
Two in the morning, 7:04 AM to 11:15 AM, then one evening flight at 7:31 PM.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Knoxville to Washington
American Airlines is the only airline flying nonstop from Knoxville to Washington, 2 to 3 times a day on the CRJ 700 and CRJ 900.
There are 2 or 3 flights every day of the week. The first arrival in Washington is at 8:57 AM and the last at 9:23 PM. The flight covers 436 miles.
Flying back, Washington to Knoxville has 20 nonstop flights a week. From Knoxville, Dulles (IAD) and Baltimore (BWI) are the other Washington area airports with nonstop flights, 26 and 7 a week.
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Schedules as of Oct 9, 2026.