Nonstop flights from Washington to Knoxville
American Airlines flies this route 2 to 3 times a day.
DCARonald Reagan Washington National
436 mi · 20 flights a week
TYSKnoxville McGhee Tyson
When they leave
Washington time9:00a7:46pFirst departure 9:00 AM, last 7:46 PM
One morning flight at 9:00 AM, then two in the evening, 5:14 PM to 7:46 PM.
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Schedules last checked Sep 19, 2026. Times are local.
Flying from Washington to Knoxville
American Airlines is the only airline flying nonstop from Washington to Knoxville, 2 to 3 times a day on the CRJ 700 and CRJ 900.
There are 2 or 3 flights every day of the week. The first arrival in Knoxville is at 10:45 AM and the last at 9:34 PM. The flight covers 436 miles.
Flying back, Knoxville to Washington has 20 nonstop flights a week. Dulles (IAD) and Baltimore (BWI) also have nonstop flights to Knoxville, 26 and 7 a week.
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Schedules as of Oct 9, 2026.