Nonstop flights from New York to Knoxville
Delta Air Lines flies this route 2 to 3 times a day.
LGANew York LaGuardia
647 mi · 20 flights a week
TYSKnoxville McGhee Tyson
When they leave
New York time8:44a6:55pFirst departure 8:44 AM, last 6:55 PM
One morning flight at 8:44 AM, then one afternoon flight at 2:15 PM, then one evening flight at 6:55 PM.
Every flight
Earliest first
Schedules last checked Sep 8, 2026. Times are local.
Flying from New York to Knoxville
Delta Air Lines is the only airline flying nonstop from New York to Knoxville, 2 to 3 times a day on the CRJ 900.
There are 2 or 3 flights every day of the week. The first arrival in Knoxville is at 10:58 AM and the last at 9:29 PM. The flight covers 647 miles.
Flying back, Knoxville to New York has 20 nonstop flights a week. Newark (EWR) also has nonstop flights to Knoxville, 17 a week.
Return flights
Every New York airport
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Schedules as of Oct 9, 2026.