Nonstop flights from Philadelphia to Knoxville
2 airlines fly this route, with up to 4 flights a day.
PHLPhiladelphia International
554 mi · 23 flights a week
TYSKnoxville McGhee Tyson
When they leave
Philadelphia time8:30a5:59pFirst departure 8:30 AM, last 5:59 PM
One morning flight at 8:30 AM, then two in the afternoon, 3:50 PM to 4:35 PM, then two in the evening, 5:36 PM to 5:59 PM.
Every flight
Earliest first
Schedules last checked Sep 20, 2026. Times are local.
Flying from Philadelphia to Knoxville
American Airlines flies most often, 3 times a day on the Embraer ERJ-145 and CRJ 900. Allegiant Air flies on Fridays and Sundays with the Airbus A320 and Boeing 737 MAX 8.
Flights run every day of the week, 4 on Fridays and Sundays and 3 on the other days. The first arrival in Knoxville is at 10:43 AM and the last at 8:07 PM. The flight covers 554 miles.
Flying back, Knoxville to Philadelphia has 19 nonstop flights a week.
Return flights
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Find the cheapest day to fly from Philadelphia to Knoxville.
Schedules as of Oct 9, 2026.