Nonstop flights from Knoxville to Orlando

2 airlines fly this route, with up to 2 flights a day.

TYSKnoxville McGhee Tyson

533 mi · 9 flights a week

MCOOrlando International

TYSMCO

When they leave

Knoxville time

12:30p6:29pFirst departure 12:30 PM, last 6:29 PM

Five in the afternoon, 12:30 PM to 2:51 PM, then one evening flight at 6:29 PM.

Every flight

Earliest first

12:30 PM→2:20 PMSouthwest AirlinesBoeing 737-700Sat
12:45 PM→2:35 PMSouthwest AirlinesBoeing 737Tue, Wed
1:00 PM→2:50 PMSouthwest AirlinesBoeing 737 MAX 8Mon, Thu, Fri
1:15 PM→3:05 PMSouthwest AirlinesBoeing 737-700Sun
2:51 PM→4:33 PMAllegiant AirAirbus A320Fri
6:29 PM→8:07 PMAllegiant AirAirbus A320Mon

Schedules last checked Sep 20, 2026. Times are local.

Flying from Knoxville to Orlando

Southwest Airlines flies most often, daily on the Boeing 737-700, Boeing 737 and Boeing 737 MAX 8. Allegiant Air flies on Mondays and Fridays with the Airbus A320.

Flights run every day of the week, 2 on Mondays and Fridays and 1 on the other days. The first arrival in Orlando is at 2:20 PM and the last at 8:07 PM. The flight covers 533 miles.

Flying back, Orlando to Knoxville has 9 nonstop flights a week. From Knoxville, Sanford (SFB) is the other Orlando area airport with nonstop flights, 2 a week.