Nonstop flights from Minneapolis to Knoxville
Delta Air Lines flies this route 1 to 2 times a day.
MSPMinneapolis-Saint Paul International
792 mi · 13 flights a week
TYSKnoxville McGhee Tyson
When they leave
Minneapolis time1:25p7:45pFirst departure 1:25 PM, last 7:45 PM
One afternoon flight at 1:25 PM, then one evening flight at 7:45 PM.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Minneapolis to Knoxville
Delta Air Lines is the only airline flying nonstop from Minneapolis to Knoxville, 1 to 2 times a day on the CRJ 700 and CRJ 900.
There are 1 or 2 flights every day of the week. The first arrival in Knoxville is at 4:41 PM and the last at 11:00 PM. The flight covers 792 miles.
Flying back, Knoxville to Minneapolis has 13 nonstop flights a week.
Return flights
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Find the cheapest day to fly from Minneapolis to Knoxville.
Schedules as of Oct 9, 2026.