Nonstop flights from Destin to Knoxville

Allegiant Air flies this route 1 to 2 times a day until Jan 3, 2027, then again from Mar 4, 2027.

VPSDestin-Fort Walton Beach

396 mi · 9 flights a week

TYSKnoxville McGhee Tyson

VPSTYS

When they leave

Destin time

2:01p9:13pFirst departure 2:01 PM, last 9:13 PM

Five in the afternoon, 2:01 PM to 4:49 PM, then three in the evening, 7:59 PM to 9:13 PM.

Every flight

Earliest first

2:01 PM→4:22 PMAllegiant AirUntil Jan 3, 2027, back Mar 4, 2027Airbus A320Mon
3:03 PM→5:25 PMAllegiant AirUntil Jan 3, 2027, back Mar 4, 2027Airbus A320Tue
3:41 PM→6:03 PMAllegiant AirUntil Jan 3, 2027, back Mar 4, 2027Airbus A320Sat
4:04 PM→6:25 PMAllegiant AirUntil Jan 3, 2027, back Mar 4, 2027Airbus A320Wed
4:49 PM→7:11 PMAllegiant AirUntil Jan 3, 2027, back Mar 4, 2027Airbus A320Fri, Sun
7:59 PM→10:20 PMAllegiant AirUntil Jan 3, 2027, back Mar 4, 2027Airbus A320Mon
9:05 PM→11:27 PMAllegiant AirUntil Jan 3, 2027, back Mar 4, 2027Airbus A320Thu
9:13 PM→11:34 PMAllegiant AirUntil Jan 3, 2027, back Mar 4, 2027Airbus A320Fri

Schedules last checked Sep 19, 2026. Times are local.

Flying from Destin to Knoxville

Allegiant Air is the only airline flying nonstop from Destin to Knoxville, 1 to 2 times a day on the Airbus A320.

Flights run every day of the week, 2 on Mondays and Fridays and 1 on the other days. The first arrival in Knoxville is at 4:22 PM and the last at 11:34 PM. The flight covers 396 miles.

Flying back, Knoxville to Destin has 9 nonstop flights a week.

Return flights

Knoxville to DestinView

Find the cheapest day to fly from Destin to Knoxville.

Schedules as of Oct 9, 2026.